The Psychosocial Readiness Evaluation and Preparation for Hepatitis C Treatment (PREP-C) is a free interactive online tool that enables you to provide a thorough assessment of a patient’s psychosocial readiness to begin Hepatitis C treatment, and make a treatment plan to improve treatment readiness.

This free online tool can be used by any type of professional involved in preparing a patient for Hepatitis C Treatment including medical providers, nurses, mental health, substance use, social work, pharmacy, case management, treatment adherence and health education specialists.

We invite you to learn more about the PREP-C in the About and Training sections. We hope that after doing so you will Register as a user and begin to use the PREP-C to help your patients prepare to start Hepatitis C treatment.



Mon, Feb 3rd 2014, 12:10

In light of the recent therapeutic advances in the treatment of Hepatitis C which have shortened the length of the treatment course, patient readiness is now more important than ever before.

This site has been updated to incorporate the two new HCV medications recently FDA approved. In addition, in response to request from PREP-C users for a shorter version, we have created an abbreviated version which can be administered instead of the full version. We invite you to explore these new features.

Login Register


  • The information you will enter to determine your patient’s readiness to begin Hepatitis C Treatment is secure and you do not need to enter your patient’s name or any other personal identification.

Registration for the PREP- C is quick, easy & free.

In order to register, you will need to enter basic information about your professional role, and read and agree to the web site’s Terms of Use and Privacy Policy.

  • Once you have completed the registration, your information will be reviewed by PREP-C staff and you will be notified within one business day whether your account has been approved.
  • Once your registration has been approved, you can use the PREP-C online tool to administer the PREP-C interview to your patients.

What you can expect from the PREP-C

  • The online tool will provide feedback as to how to improve your patient’s readiness to begin Hepatitis C treatment based on the information you enter.
  • Your completed interviews will be stored in the Healthcare Provider Portal, which allow you to record a treatment plan and return to re-administer sections of the PREP-C at a later time.
  • You can print out a copy of your completed interviews from this web site to use for the patient’s medical record.